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  1. Tam, OH, Rozhkov, NV, Shaw, R, Kim, D, Hubbard, I, Fennessey, S, Propp, N, NYGC ALS Consortium, Fagegaltier, D, Harris, BT, Ostrow, LW, Phatnani, H, Ravits, J, Dubnau, J, Gale Hammell, M. 2019. Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia. Cell Rep 29:1164-1177.e5.
  2. International Multiple Sclerosis Genetics Consortium. 2019. Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility. Science 365:.
  3. Izzy, S, Liu, Q, Fang, Z, Lule, S, Wu, L, Chung, JY, Sarro-Schwartz, A, Brown-Whalen, A, Perner, C, Hickman, SE, Kaplan, DL, Patsopoulos, NA, El Khoury, J, Whalen, MJ. 2019. Time-Dependent Changes in Microglia Transcriptional Networks Following Traumatic Brain Injury. Front Cell Neurosci 13:307.
  4. Beecham, AH, Amezcua, L, Chinea, A, Manrique, CP, Rubi, C, Isobe, N, Lund, BT, Santaniello, A, Beecham, GW, Burchard, EG, Comabella, M, Patsopoulos, N, Fitzgerald, K, Calabresi, PA, De Jager, P, Conti, DV, Delgado, SR, Oksenberg, JR, McCauley, JL. 2020. The genetic diversity of multiple sclerosis risk among Hispanic and African American populations living in the United States. Mult Scler 26:1329-1339.
  5. International Multiple Sclerosis Genetics Consortium. 2019. Author Correction: A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis. Nat Commun 10:2956.
  6. International Multiple Sclerosis Genetics Consortium. Electronic address: chris.cotsapas@yale.edu, International Multiple Sclerosis Genetics Consortium. 2019. Low-Frequency and Rare-Coding Variation Contributes to Multiple Sclerosis Risk. Cell 178:262.
  7. Currall, BB, Chen, M, Sallari, RC, Cotter, M, Wong, KE, Robertson, NG, Penney, KL, Lunardi, A, Reschke, M, Hickox, AE, Yin, Y, Wong, GT, Fung, J, Brown, KK, Williamson, RE, Sinnott-Armstrong, NA, Kammin, T, Ivanov, A, Zepeda-Mendoza, CJ, Shen, J, Quade, BJ, Signoretti, S, Arnos, KS, Banks, AS, Patsopoulos, N, Liberman, MC, Kellis, M, Pandolfi, PP, Morton, CC. 2019. Corrigendum: Loss of LDAH associated with prostate cancer and hearing loss. Hum Mol Genet 28:1753-1754.
  8. International Multiple Sclerosis Genetics Consortium. 2019. A systems biology approach uncovers cell-specific gene regulatory effects of genetic associations in multiple sclerosis. Nat Commun 10:2236.
  9. Cruz, GI, Shao, X, Quach, H, Quach, D, Ho, KA, Sterba, K, Noble, JA, Patsopoulos, NA, Busch, MP, Triulzi, DJ, Ladas, N, Blasczyk, R, Wong, WSW, Solomon, BD, Niederhuber, JE, Criswell, LA, Barcellos, LF. 2020. Mother-child histocompatibility and risk of rheumatoid arthritis and systemic lupus erythematosus among mothers. Genes Immun 21:27-36.
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  1. International Multiple Sclerosis Genetics Consortium. Electronic address: chris.cotsapas@yale.edu, International Multiple Sclerosis Genetics Consortium. 2018. Low-Frequency and Rare-Coding Variation Contributes to Multiple Sclerosis Risk. Cell 175:1679-1687.e7.
  2. Currall, BB, Chen, M, Sallari, RC, Cotter, M, Wong, KE, Robertson, NG, Penney, KL, Lunardi, A, Reschke, M, Hickox, AE, Yin, Y, Wong, GT, Fung, J, Brown, KK, Williamson, RE, Sinnott-Armstrong, NA, Kammin, T, Ivanov, A, Zepeda-Mendoza, CJ, Shen, J, Quade, BJ, Signoretti, S, Arnos, KS, Banks, AS, Patsopoulos, N, Liberman, MC, Kellis, M, Pandolfi, PP, Morton, CC. 2018. Loss of LDAH associated with prostate cancer and hearing loss. Hum Mol Genet 27:4194-4203.
  3. Haghighi, A, Krier, JB, Toth-Petroczy, A, Cassa, CA, Frank, NY, Carmichael, N, Fieg, E, Bjonnes, A, Mohanty, A, Briere, LC, Lincoln, S, Lucia, S, Gupta, VA, Söylemez, O, Sutti, S, Kooshesh, K, Qiu, H, Fay, CJ, Perroni, V, Valerius, J, Hanna, M, Frank, A, Ouahed, J, Snapper, SB, Pantazi, A, Chopra, SS, Leshchiner, I, Stitziel, NO, Feldweg, A, Mannstadt, M, Loscalzo, J, Sweetser, DA, Liao, E, Stoler, JM, Nowak, CB, Sanchez-Lara, PA, Klein, OD, Perry, H, Patsopoulos, NA, Raychaudhuri, S, Goessling, W, Green, RC, Seidman, CE, MacRae, CA, Sunyaev, SR, Maas, RL, Vuzman, D, Undiagnosed Diseases Network, Brigham and Women’s Hospital FaceBase Project, Brigham Genomic Medicine (BGM). 2018. An integrated clinical program and crowdsourcing strategy for genomic sequencing and Mendelian disease gene discovery. NPJ Genom Med 3:21.
  4. Felsky, D, Patrick, E, Schneider, JA, Mostafavi, S, Gaiteri, C, Patsopoulos, N, Bennett, DA, De Jager, PL. 2018. Polygenic analysis of inflammatory disease variants and effects on microglia in the aging brain. Mol Neurodegener 13:38.
  5. Conlon, EG, Fagegaltier, D, Agius, P, Davis-Porada, J, Gregory, J, Hubbard, I, Kang, K, Kim, D, New York Genome Center ALS Consortium, Phatnani, H, Shneider, NA, Manley, JL. 2018. Unexpected similarities between C9ORF72 and sporadic forms of ALS/FTD suggest a common disease mechanism. Elife 7:.
  6. Brainstorm Consortium, Anttila, V, Bulik-Sullivan, B, Finucane, HK, Walters, RK, Bras, J, Duncan, L, Escott-Price, V, Falcone, GJ, Gormley, P, Malik, R, Patsopoulos, NA, Ripke, S, Wei, Z, Yu, D, Lee, PH, Turley, P, Grenier-Boley, B, Chouraki, V, Kamatani, Y, Berr, C, Letenneur, L, Hannequin, D, Amouyel, P, Boland, A, Deleuze, JF, Duron, E, Vardarajan, BN, Reitz, C, Goate, AM, Huentelman, MJ, Kamboh, MI, Larson, EB, Rogaeva, E, St George-Hyslop, P, Hakonarson, H, Kukull, WA, Farrer, LA, Barnes, LL, Beach, TG, Demirci, FY, Head, E, Hulette, CM, Jicha, GA, Kauwe, JSK, Kaye, JA, Leverenz, JB, Levey, AI, Lieberman, AP, Pankratz, VS, Poon, WW, Quinn, JF, Saykin, AJ, Schneider, LS, Smith, AG, Sonnen, JA, Stern, RA, Van Deerlin, VM, Van Eldik, LJ, Harold, D, Russo, G, Rubinsztein, DC, Bayer, A, Tsolaki, M, Proitsi, P, Fox, NC, Hampel, H, Owen, MJ, Mead, S, Passmore, P, Morgan, K, Nöthen, MM, Rossor, M, Lupton, MK, Hoffmann, P, Kornhuber, J, Lawlor, B, McQuillin, A, Al-Chalabi, A, Bis, JC, Ruiz, A, Boada, M, Seshadri, S, Beiser, A, Rice, K, van der Lee, SJ, De Jager, PL, Geschwind, DH, Riemenschneider, M, Riedel-Heller, S, Rotter, JI, Ransmayr, G, Hyman, BT, Cruchaga, C, Alegret, M, Winsvold, B, Palta, P, Farh, KH, Cuenca-Leon, E et al.. 2018. Analysis of shared heritability in common disorders of the brain. Science 360:.
  7. Nicolas, A, Kenna, KP, Renton, AE, Ticozzi, N, Faghri, F, Chia, R, Dominov, JA, Kenna, BJ, Nalls, MA, Keagle, P, Rivera, AM, van Rheenen, W, Murphy, NA, van Vugt, JJFA, Geiger, JT, Van der Spek, RA, Pliner, HA, Shankaracharya,, Smith, BN, Marangi, G, Topp, SD, Abramzon, Y, Gkazi, AS, Eicher, JD, Kenna, A, ITALSGEN Consortium, Mora, G, Calvo, A, Mazzini, L, Riva, N, Mandrioli, J, Caponnetto, C, Battistini, S, Volanti, P, La Bella, V, Conforti, FL, Borghero, G, Messina, S, Simone, IL, Trojsi, F, Salvi, F, Logullo, FO, D'Alfonso, S, Corrado, L, Capasso, M, Ferrucci, L, Genomic Translation for ALS Care (GTAC) Consortium, Moreno, CAM, Kamalakaran, S, Goldstein, DB, ALS Sequencing Consortium, Gitler, AD, Harris, T, Myers, RM, NYGC ALS Consortium, Phatnani, H, Musunuri, RL, Evani, US, Abhyankar, A, Zody, MC, Answer ALS Foundation, Kaye, J, Finkbeiner, S, Wyman, SK, LeNail, A, Lima, L, Fraenkel, E, Svendsen, CN, Thompson, LM, Van Eyk, JE, Berry, JD, Miller, TM, Kolb, SJ, Cudkowicz, M, Baxi, E, Clinical Research in ALS and Related Disorders for Therapeutic Development (CReATe) Consortium, Benatar, M, Taylor, JP, Rampersaud, E, Wu, G, Wuu, J, SLAGEN Consortium, Lauria, G, Verde, F, Fogh, I, Tiloca, C, Comi, GP, Sorarù, G, Cereda, C, French ALS Consortium, Corcia, P, Laaksovirta, H, Myllykangas, L, Jansson, L, Valori, M, Ealing, J, Hamdalla, H, Rollinson, S, Pickering-Brown, S et al.. 2018. Genome-wide Analyses Identify KIF5A as a Novel ALS Gene. Neuron 97:1268-1283.e6.
  8. Patsopoulos, NA. 2018. Genetics of Multiple Sclerosis: An Overview and New Directions. Cold Spring Harb Perspect Med 8:.
  9. Kaskow, BJ, Buttrick, TS, Klein, HU, White, C, Bourgeois, JR, Ferland, RJ, Patsopoulos, N, Bradshaw, EM, De Jager, PL, Elyaman, W. 2018. MS AHI1 genetic risk promotes IFNγ+ CD4+ T cells. Neurol Neuroimmunol Neuroinflamm 5:e414.
  10. Rappoport, N, Toung, J, Hadley, D, Wong, RJ, Fujioka, K, Reuter, J, Abbott, CW, Oh, S, Hu, D, Eng, C, Huntsman, S, Bodian, DL, Niederhuber, JE, Hong, X, Zhang, G, Sikora-Wohfeld, W, Gignoux, CR, Wang, H, Oehlert, J, Jelliffe-Pawlowski, LL, Gould, JB, Darmstadt, GL, Wang, X, Bustamante, CD, Snyder, MP, Ziv, E, Patsopoulos, NA, Muglia, LJ, Burchard, E, Shaw, GM, O'Brodovich, HM, Stevenson, DK, Butte, AJ, Sirota, M. 2018. A genome-wide association study identifies only two ancestry specific variants associated with spontaneous preterm birth. Sci Rep 8:226.
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  1. Kaskow, BJ, Buttrick, TS, Klein, HU, White, C, Bourgeois, JR, Ferland, RJ, Patsopoulos, N, Bradshaw, EM, De Jager, PL, Elyaman, W. 2018. MS AHI1 genetic risk promotes IFNγ+ CD4+ T cells. Neurol Neuroimmunol Neuroinflamm 5:e414.
  2. Cruz, GI, Shao, X, Quach, H, Ho, KA, Sterba, K, Noble, JA, Patsopoulos, NA, Busch, MP, Triulzi, DJ, Wong, WS, Solomon, BD, Niederhuber, JE, Criswell, LA, Barcellos, LF. 2017. Increased risk of rheumatoid arthritis among mothers with children who carry DRB1 risk-associated alleles. Ann Rheum Dis 76:1405-1410.
  3. Chun, S, Casparino, A, Patsopoulos, NA, Croteau-Chonka, DC, Raby, BA, De Jager, PL, Sunyaev, SR, Cotsapas, C. 2017. Limited statistical evidence for shared genetic effects of eQTLs and autoimmune-disease-associated loci in three major immune-cell types. Nat Genet 49:600-605.
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  1. Cruz, GI, Shao, X, Quach, H, Ho, KA, Sterba, K, Noble, JA, Patsopoulos, NA, Busch, MP, Triulzi, DJ, Wong, WS, Solomon, BD, Niederhuber, JE, Criswell, LA, Barcellos, LF. 2016. A Child's HLA-DRB1 genotype increases maternal risk of systemic lupus erythematosus. J Autoimmun 74:201-207.
  2. International Multiple Sclerosis Genetics Consortium. Electronic address: cotsapas@broadinstitute.org, International Multiple Sclerosis Genetics Consortium. 2016. NR1H3 p.Arg415Gln Is Not Associated to Multiple Sclerosis Risk. Neuron 92:333-335.
  3. George, MF, Briggs, FB, Shao, X, Gianfrancesco, MA, Kockum, I, Harbo, HF, Celius, EG, Bos, SD, Hedström, A, Shen, L, Bernstein, A, Alfredsson, L, Hillert, J, Olsson, T, Patsopoulos, NA, De Jager, PL, Oturai, AB, Søndergaard, HB, Sellebjerg, F, Sorensen, PS, Gomez, R, Caillier, SJ, Cree, BA, Oksenberg, JR, Hauser, SL, D'Alfonso, S, Leone, MA, Martinelli Boneschi, F, Sorosina, M, van der Mei, I, Taylor, BV, Zhou, Y, Schaefer, C, Barcellos, LF. 2016. Multiple sclerosis risk loci and disease severity in 7,125 individuals from 10 studies. Neurol Genet 2:e87.
  4. Epstein, T, Patsopoulos, NA, Weiser, M. 2016. WITHDRAWN: Immediate-release methylphenidate for attention deficit hyperactivity disorder (ADHD) in adults. Cochrane Database Syst Rev :CD005041.
  5. Brown, BC, Price, AL, Patsopoulos, NA, Zaitlen, N. 2016. Local Joint Testing Improves Power and Identifies Hidden Heritability in Association Studies. Genetics 203:1105-16.
  6. Zhou, Y, Zhu, G, Charlesworth, JC, Simpson, S Jr, Rubicz, R, Göring, HH, Patsopoulos, NA, Laverty, C, Wu, F, Henders, A, Ellis, JJ, van der Mei, I, Montgomery, GW, Blangero, J, Curran, JE, Johnson, MP, Martin, NG, Nyholt, DR, Taylor, BV, ANZgene consortium. 2016. Genetic loci for Epstein-Barr virus nuclear antigen-1 are associated with risk of multiple sclerosis. Mult Scler 22:1655-1664.
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  1. Didonna, A, Isobe, N, Caillier, SJ, Li, KH, Burlingame, AL, Hauser, SL, Baranzini, SE, Patsopoulos, NA, Oksenberg, JR. 2015. A non-synonymous single-nucleotide polymorphism associated with multiple sclerosis risk affects the EVI5 interactome. Hum Mol Genet 24:7151-8.
  2. Vilhjálmsson, BJ, Yang, J, Finucane, HK, Gusev, A, Lindström, S, Ripke, S, Genovese, G, Loh, PR, Bhatia, G, Do, R, Hayeck, T, Won, HH, Schizophrenia Working Group of the Psychiatric Genomics Consortium, Discovery, Biology, and Risk of Inherited Variants in Breast Cancer (DRIVE) study, Kathiresan, S, Pato, M, Pato, C, Tamimi, R, Stahl, E, Zaitlen, N, Pasaniuc, B, Belbin, G, Kenny, EE, Schierup, MH, De Jager, P, Patsopoulos, NA, McCarroll, S, Daly, M, Purcell, S, Chasman, D, Neale, B, Goddard, M, Visscher, PM, Kraft, P, Patterson, N, Price, AL. 2015. Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores. Am J Hum Genet 97:576-92.
  3. Moutsianas, L, Jostins, L, Beecham, AH, Dilthey, AT, Xifara, DK, Ban, M, Shah, TS, Patsopoulos, NA, Alfredsson, L, Anderson, CA, Attfield, KE, Baranzini, SE, Barrett, J, Binder, TMC, Booth, D, Buck, D, Celius, EG, Cotsapas, C, D'Alfonso, S, Dendrou, CA, Donnelly, P, Dubois, B, Fontaine, B, Fugger, L, Goris, A, Gourraud, PA, Graetz, C, Hemmer, B, Hillert, J, International IBD Genetics Consortium (IIBDGC), Kockum, I, Leslie, S, Lill, CM, Martinelli-Boneschi, F, Oksenberg, JR, Olsson, T, Oturai, A, Saarela, J, Søndergaard, HB, Spurkland, A, Taylor, B, Winkelmann, J, Zipp, F, Haines, JL, Pericak-Vance, MA, Spencer, CCA, Stewart, G, Hafler, DA, Ivinson, AJ, Harbo, HF, Hauser, SL, De Jager, PL, Compston, A, McCauley, JL, Sawcer, S, McVean, G. 2015. Class II HLA interactions modulate genetic risk for multiple sclerosis. Nat Genet 47:1107-1113.
  4. Hilven, K, Patsopoulos, NA, Dubois, B, Goris, A. 2015. Burden of risk variants correlates with phenotype of multiple sclerosis. Mult Scler 21:1670-80.
  5. Esposito, F, Sorosina, M, Ottoboni, L, Lim, ET, Replogle, JM, Raj, T, Brambilla, P, Liberatore, G, Guaschino, C, Romeo, M, Pertel, T, Stankiewicz, JM, Martinelli, V, Rodegher, M, Weiner, HL, Brassat, D, Benoist, C, Patsopoulos, NA, Comi, G, Elyaman, W, Martinelli Boneschi, F, De Jager, PL. 2015. A pharmacogenetic study implicates SLC9a9 in multiple sclerosis disease activity. Ann Neurol 78:115-27.
  6. Farh, KK, Marson, A, Zhu, J, Kleinewietfeld, M, Housley, WJ, Beik, S, Shoresh, N, Whitton, H, Ryan, RJ, Shishkin, AA, Hatan, M, Carrasco-Alfonso, MJ, Mayer, D, Luckey, CJ, Patsopoulos, NA, De Jager, PL, Kuchroo, VK, Epstein, CB, Daly, MJ, Hafler, DA, Bernstein, BE. 2015. Genetic and epigenetic fine mapping of causal autoimmune disease variants. Nature 518:337-43.
  7. Andreassen, OA, Harbo, HF, Wang, Y, Thompson, WK, Schork, AJ, Mattingsdal, M, Zuber, V, Bettella, F, Ripke, S, Kelsoe, JR, Kendler, KS, O'Donovan, MC, Sklar, P, Psychiatric Genomics Consortium (PGC) Bipolar Disorder and Schizophrenia Work Groups, International Multiple Sclerosis Genetics Consortium (IMSGC), McEvoy, LK, Desikan, RS, Lie, BA, Djurovic, S, Dale, AM. 2015. Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene loci. Mol Psychiatry 20:207-14.
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  1. Farh, KK, Marson, A, Zhu, J, Kleinewietfeld, M, Housley, WJ, Beik, S, Shoresh, N, Whitton, H, Ryan, RJ, Shishkin, AA, Hatan, M, Carrasco-Alfonso, MJ, Mayer, D, Luckey, CJ, Patsopoulos, NA, De Jager, PL, Kuchroo, VK, Epstein, CB, Daly, MJ, Hafler, DA, Bernstein, BE. 2015. Genetic and epigenetic fine mapping of causal autoimmune disease variants. Nature 518:337-43.
  2. Epstein, T, Patsopoulos, NA, Weiser, M. 2014. Immediate-release methylphenidate for attention deficit hyperactivity disorder (ADHD) in adults. Cochrane Database Syst Rev :CD005041.
  3. Paraboschi, EM, Rimoldi, V, Soldà, G, Tabaglio, T, Dall'Osso, C, Saba, E, Vigliano, M, Salviati, A, Leone, M, Benedetti, MD, Fornasari, D, Saarela, J, De Jager, PL, Patsopoulos, NA, D'Alfonso, S, Gemmati, D, Duga, S, Asselta, R. 2014. Functional variations modulating PRKCA expression and alternative splicing predispose to multiple sclerosis. Hum Mol Genet 23:6746-61.
  4. Raj, T, Rothamel, K, Mostafavi, S, Ye, C, Lee, MN, Replogle, JM, Feng, T, Lee, M, Asinovski, N, Frohlich, I, Imboywa, S, Von Korff, A, Okada, Y, Patsopoulos, NA, Davis, S, McCabe, C, Paik, HI, Srivastava, GP, Raychaudhuri, S, Hafler, DA, Koller, D, Regev, A, Hacohen, N, Mathis, D, Benoist, C, Stranger, BE, De Jager, PL. 2014. Polarization of the effects of autoimmune and neurodegenerative risk alleles in leukocytes. Science 344:519-23.
  5. Sundqvist, E, Buck, D, Warnke, C, Albrecht, E, Gieger, C, Khademi, M, Lima Bomfim, I, Fogdell-Hahn, A, Link, J, Alfredsson, L, Søndergaard, HB, Hillert, J, International Multiple Sclerosis Genetics Consortium, Oturai, AB, Hemmer, B, Hemme, B, Kockum, I, Olsson, T. 2014. JC polyomavirus infection is strongly controlled by human leucocyte antigen class II variants. PLoS Pathog 10:e1004084.
  6. Andreassen, OA, Harbo, HF, Wang, Y, Thompson, WK, Schork, AJ, Mattingsdal, M, Zuber, V, Bettella, F, Ripke, S, Kelsoe, JR, Kendler, KS, O'Donovan, MC, Sklar, P, Psychiatric Genomics Consortium (PGC) Bipolar Disorder and Schizophrenia Work Groups, International Multiple Sclerosis Genetics Consortium (IMSGC), McEvoy, LK, Desikan, RS, Lie, BA, Djurovic, S, Dale, AM. 2015. Genetic pleiotropy between multiple sclerosis and schizophrenia but not bipolar disorder: differential involvement of immune-related gene loci. Mol Psychiatry 20:207-14.
  7. Damotte, V, Guillot-Noel, L, Patsopoulos, NA, Madireddy, L, El Behi, M, International Multiple Sclerosis Genetics Consortium, Wellcome Trust Case Control Consortium 2, De Jager, PL, Baranzini, SE, Cournu-Rebeix, I, Fontaine, B. 2014. A gene pathway analysis highlights the role of cellular adhesion molecules in multiple sclerosis susceptibility. Genes Immun 15:126-32.
  8. Goris, A, van Setten, J, Diekstra, F, Ripke, S, Patsopoulos, NA, Sawcer, SJ, International Multiple Sclerosis Genetics Consortium, van Es, M, Australia and New Zealand MS Genetics Consortium, Andersen, PM, Melki, J, Meininger, V, Hardiman, O, Landers, JE, Brown, RH Jr, Shatunov, A, Leigh, N, Al-Chalabi, A, Shaw, CE, Traynor, BJ, Chiò, A, Restagno, G, Mora, G, Ophoff, RA, Oksenberg, JR, Van Damme, P, Compston, A, Robberecht, W, Dubois, B, van den Berg, LH, De Jager, PL, Veldink, JH, de Bakker, PI. 2014. No evidence for shared genetic basis of common variants in multiple sclerosis and amyotrophic lateral sclerosis. Hum Mol Genet 23:1916-22.
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  1. Patsopoulos, NA, Barcellos, LF, Hintzen, RQ, Schaefer, C, van Duijn, CM, Noble, JA, Raj, T, IMSGC, ANZgene, Gourraud, PA, Stranger, BE, Oksenberg, J, Olsson, T, Taylor, BV, Sawcer, S, Hafler, DA, Carrington, M, De Jager, PL, de Bakker, PI. 2013. Fine-mapping the genetic association of the major histocompatibility complex in multiple sclerosis: HLA and non-HLA effects. PLoS Genet 9:e1003926.
  2. Goris, A, van Setten, J, Diekstra, F, Ripke, S, Patsopoulos, NA, Sawcer, SJ, International Multiple Sclerosis Genetics Consortium, van Es, M, Australia and New Zealand MS Genetics Consortium, Andersen, PM, Melki, J, Meininger, V, Hardiman, O, Landers, JE, Brown, RH Jr, Shatunov, A, Leigh, N, Al-Chalabi, A, Shaw, CE, Traynor, BJ, Chiò, A, Restagno, G, Mora, G, Ophoff, RA, Oksenberg, JR, Van Damme, P, Compston, A, Robberecht, W, Dubois, B, van den Berg, LH, De Jager, PL, Veldink, JH, de Bakker, PI. 2014. No evidence for shared genetic basis of common variants in multiple sclerosis and amyotrophic lateral sclerosis. Hum Mol Genet 23:1916-22.
  3. Wissemann, WT, Hill-Burns, EM, Zabetian, CP, Factor, SA, Patsopoulos, N, Hoglund, B, Holcomb, C, Donahue, RJ, Thomson, G, Erlich, H, Payami, H. 2013. Association of Parkinson disease with structural and regulatory variants in the HLA region. Am J Hum Genet 93:984-93.
  4. International Multiple Sclerosis Genetics Consortium (IMSGC), Beecham, AH, Patsopoulos, NA, Xifara, DK, Davis, MF, Kemppinen, A, Cotsapas, C, Shah, TS, Spencer, C, Booth, D, Goris, A, Oturai, A, Saarela, J, Fontaine, B, Hemmer, B, Martin, C, Zipp, F, D'Alfonso, S, Martinelli-Boneschi, F, Taylor, B, Harbo, HF, Kockum, I, Hillert, J, Olsson, T, Ban, M, Oksenberg, JR, Hintzen, R, Barcellos, LF, Wellcome Trust Case Control Consortium 2 (WTCCC2), International IBD Genetics Consortium (IIBDGC), Agliardi, C, Alfredsson, L, Alizadeh, M, Anderson, C, Andrews, R, Søndergaard, HB, Baker, A, Band, G, Baranzini, SE, Barizzone, N, Barrett, J, Bellenguez, C, Bergamaschi, L, Bernardinelli, L, Berthele, A, Biberacher, V, Binder, TM, Blackburn, H, Bomfim, IL, Brambilla, P, Broadley, S, Brochet, B, Brundin, L, Buck, D, Butzkueven, H, Caillier, SJ, Camu, W, Carpentier, W, Cavalla, P, Celius, EG, Coman, I, Comi, G, Corrado, L, Cosemans, L, Cournu-Rebeix, I, Cree, BA, Cusi, D, Damotte, V, Defer, G, Delgado, SR, Deloukas, P, di Sapio, A, Dilthey, AT, Donnelly, P, Dubois, B, Duddy, M, Edkins, S, Elovaara, I, Esposito, F, Evangelou, N, Fiddes, B, Field, J, Franke, A, Freeman, C, Frohlich, IY, Galimberti, D, Gieger, C, Gourraud, PA, Graetz, C, Graham, A, Grummel, V, Guaschino, C, Hadjixenofontos, A, Hakonarson, H, Halfpenny, C, Hall, G, Hall, P, Hamsten, A, Harley, J et al.. 2013. Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis. Nat Genet 45:1353-60.
  5. Shulman, JM, Chen, K, Keenan, BT, Chibnik, LB, Fleisher, A, Thiyyagura, P, Roontiva, A, McCabe, C, Patsopoulos, NA, Corneveaux, JJ, Yu, L, Huentelman, MJ, Evans, DA, Schneider, JA, Reiman, EM, De Jager, PL, Bennett, DA. 2013. Genetic susceptibility for Alzheimer disease neuritic plaque pathology. JAMA Neurol 70:1150-7.
  6. International Multiple Sclerosis Genetics Consortium. 2013. Network-based multiple sclerosis pathway analysis with GWAS data from 15,000 cases and 30,000 controls. Am J Hum Genet 92:854-65.
  7. Mechelli, R, Umeton, R, Policano, C, Annibali, V, Coarelli, G, Ricigliano, VA, Vittori, D, Fornasiero, A, Buscarinu, MC, International Multiple Sclerosis Genetics Consortium, Wellcome Trust Case Control Consortium,2, Romano, S, Salvetti, M, Ristori, G. 2013. A "candidate-interactome" aggregate analysis of genome-wide association data in multiple sclerosis. PLoS One 8:e63300.
  8. Mero, IL, Gustavsen, MW, Sæther, HS, Flåm, ST, Berg-Hansen, P, Søndergaard, HB, Jensen, PE, Berge, T, Bjølgerud, A, Muggerud, A, Aarseth, JH, International Multiple Sclerosis Genetics Consortium, Myhr, KM, Celius, EG, Sellebjerg, F, Hillert, J, Alfredsson, L, Olsson, T, Oturai, AB, Kockum, I, Lie, BA, Andreassen, BK, Harbo, HF. 2013. Oligoclonal band status in Scandinavian multiple sclerosis patients is associated with specific genetic risk alleles. PLoS One 8:e58352.
  9. Veroniki, AA, Pavlides, M, Patsopoulos, NA, Salanti, G. 2013. Reconstructing 2 x 2 contingency tables from odds ratios using the Di Pietrantonj method: difficulties, constraints and impact in meta-analysis results. Res Synth Methods 4:78-94.
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  1. Veroniki, AA, Pavlides, M, Patsopoulos, NA, Salanti, G. 2013. Reconstructing 2 x 2 contingency tables from odds ratios using the Di Pietrantonj method: difficulties, constraints and impact in meta-analysis results. Res Synth Methods 4:78-94.
  2. Fung, E, Patsopoulos, NA, Belknap, SM, O'Rourke, DJ, Robb, JF, Anderson, JL, Shworak, NW, Moore, JH. 2012. Effect of genetic variants, especially CYP2C9 and VKORC1, on the pharmacology of warfarin. Semin Thromb Hemost 38:893-904.
  3. McLaren, PJ, Ripke, S, Pelak, K, Weintrob, AC, Patsopoulos, NA, Jia, X, Erlich, RL, Lennon, NJ, Kadie, CM, Heckerman, D, Gupta, N, Haas, DW, Deeks, SG, Pereyra, F, Walker, BD, de Bakker, PI, International HIV Controllers Study. 2012. Fine-mapping classical HLA variation associated with durable host control of HIV-1 infection in African Americans. Hum Mol Genet 21:4334-47.
  4. Kurreeman, FA, Stahl, EA, Okada, Y, Liao, K, Diogo, D, Raychaudhuri, S, Freudenberg, J, Kochi, Y, Patsopoulos, NA, Gupta, N, CLEAR investigators, Sandor, C, Bang, SY, Lee, HS, Padyukov, L, Suzuki, A, Siminovitch, K, Worthington, J, Gregersen, PK, Hughes, LB, Reynolds, RJ, Bridges, SL Jr, Bae, SC, Yamamoto, K, Plenge, RM. 2012. Use of a multiethnic approach to identify rheumatoid- arthritis-susceptibility loci, 1p36 and 17q12. Am J Hum Genet 90:524-32.
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  1. Patsopoulos, NA, Bayer Pharma MS Genetics Working Group, Steering Committees of Studies Evaluating IFNβ-1b and a CCR1-Antagonist, ANZgene Consortium, GeneMSA, International Multiple Sclerosis Genetics Consortium, Esposito, F, Reischl, J, Lehr, S, Bauer, D, Heubach, J, Sandbrink, R, Pohl, C, Edan, G, Kappos, L, Miller, D, Montalbán, J, Polman, CH, Freedman, MS, Hartung, HP, Arnason, BG, Comi, G, Cook, S, Filippi, M, Goodin, DS, Jeffery, D, O'Connor, P, Ebers, GC, Langdon, D, Reder, AT, Traboulsee, A, Zipp, F, Schimrigk, S, Hillert, J, Bahlo, M, Booth, DR, Broadley, S, Brown, MA, Browning, BL, Browning, SR, Butzkueven, H, Carroll, WM, Chapman, C, Foote, SJ, Griffiths, L, Kermode, AG, Kilpatrick, TJ, Lechner-Scott, J, Marriott, M, Mason, D, Moscato, P, Heard, RN, Pender, MP, Perreau, VM, Perera, D, Rubio, JP, Scott, RJ, Slee, M, Stankovich, J, Stewart, GJ, Taylor, BV, Tubridy, N, Willoughby, E, Wiley, J, Matthews, P, Boneschi, FM, Compston, A, Haines, J, Hauser, SL, McCauley, J, Ivinson, A, Oksenberg, JR, Pericak-Vance, M, Sawcer, SJ, De Jager, PL, Hafler, DA, de Bakker, PI. 2011. Genome-wide meta-analysis identifies novel multiple sclerosis susceptibility loci. Ann Neurol 70:897-912.
  2. Patsopoulos, NA. 2011. A pragmatic view on pragmatic trials. Dialogues Clin Neurosci 13:217-24.
  3. International Multiple Sclerosis Genetics Consortium, Wellcome Trust Case Control Consortium 2, Sawcer, S, Hellenthal, G, Pirinen, M, Spencer, CC, Patsopoulos, NA, Moutsianas, L, Dilthey, A, Su, Z, Freeman, C, Hunt, SE, Edkins, S, Gray, E, Booth, DR, Potter, SC, Goris, A, Band, G, Oturai, AB, Strange, A, Saarela, J, Bellenguez, C, Fontaine, B, Gillman, M, Hemmer, B, Gwilliam, R, Zipp, F, Jayakumar, A, Martin, R, Leslie, S, Hawkins, S, Giannoulatou, E, D'alfonso, S, Blackburn, H, Martinelli Boneschi, F, Liddle, J, Harbo, HF, Perez, ML, Spurkland, A, Waller, MJ, Mycko, MP, Ricketts, M, Comabella, M, Hammond, N, Kockum, I, McCann, OT, Ban, M, Whittaker, P, Kemppinen, A, Weston, P, Hawkins, C, Widaa, S, Zajicek, J, Dronov, S, Robertson, N, Bumpstead, SJ, Barcellos, LF, Ravindrarajah, R, Abraham, R, Alfredsson, L, Ardlie, K, Aubin, C, Baker, A, Baker, K, Baranzini, SE, Bergamaschi, L, Bergamaschi, R, Bernstein, A, Berthele, A, Boggild, M, Bradfield, JP, Brassat, D, Broadley, SA, Buck, D, Butzkueven, H, Capra, R, Carroll, WM, Cavalla, P, Celius, EG, Cepok, S, Chiavacci, R, Clerget-Darpoux, F, Clysters, K, Comi, G, Cossburn, M, Cournu-Rebeix, I, Cox, MB, Cozen, W, Cree, BA, Cross, AH, Cusi, D, Daly, MJ, Davis, E, de Bakker, PI, Debouverie, M, D'hooghe, MB, Dixon, K, Dobosi, R, Dubois, B et al.. 2011. Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis. Nature 476:214-9.
  4. Pereira, TV, Patsopoulos, NA, Pereira, AC, Krieger, JE. 2011. Strategies for genetic model specification in the screening of genome-wide meta-analysis signals for further replication. Int J Epidemiol 40:457-69.
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  1. Pereira, TV, Patsopoulos, NA, Pereira, AC, Krieger, JE. 2011. Strategies for genetic model specification in the screening of genome-wide meta-analysis signals for further replication. Int J Epidemiol 40:457-69.
  2. International Multiple Sclerosis Genetics Conssortium (IMSGC). 2010. IL12A, MPHOSPH9/CDK2AP1 and RGS1 are novel multiple sclerosis susceptibility loci. Genes Immun 11:397-405.
  3. Siontis, GC, Patsopoulos, NA, Vlahos, AP, Ioannidis, JP. 2010. Selection and presentation of imaging figures in the medical literature. PLoS One 5:e10888.
  4. Pereira, TV, Patsopoulos, NA, Salanti, G, Ioannidis, JP. 2010. Critical interpretation of Cochran's Q test depends on power and prior assumptions about heterogeneity. Res Synth Methods 1:149-61.
  5. Siontis, KC, Patsopoulos, NA, Ioannidis, JP. 2010. Replication of past candidate loci for common diseases and phenotypes in 100 genome-wide association studies. Eur J Hum Genet 18:832-7.
  6. Valachis, A, Polyzos, NP, Patsopoulos, NA, Georgoulias, V, Mavroudis, D, Mauri, D. 2010. Bevacizumab in metastatic breast cancer: a meta-analysis of randomized controlled trials. Breast Cancer Res Treat 122:1-7.
  7. Lathyris, DN, Patsopoulos, NA, Salanti, G, Ioannidis, JP. 2010. Industry sponsorship and selection of comparators in randomized clinical trials. Eur J Clin Invest 40:172-82.
  8. Patsopoulos, NA, Ioannidis, JP. 2010. Susceptibility variants for rheumatoid arthritis in the TRAF1-C5 and 6q23 loci: a meta-analysis. Ann Rheum Dis 69:561-6.
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  1. Lathyris, DN, Patsopoulos, NA, Salanti, G, Ioannidis, JP. 2010. Industry sponsorship and selection of comparators in randomized clinical trials. Eur J Clin Invest 40:172-82.
  2. Patsopoulos, NA, Ioannidis, JP. 2009. The use of older studies in meta-analyses of medical interventions: a survey. Open Med 3:e62-8.
  3. Pereira, TV, Patsopoulos, NA, Salanti, G, Ioannidis, JP. 2009. Discovery properties of genome-wide association signals from cumulatively combined data sets. Am J Epidemiol 170:1197-206.
  4. Patsopoulos, NA, Ioannidis, JP. 2010. Susceptibility variants for rheumatoid arthritis in the TRAF1-C5 and 6q23 loci: a meta-analysis. Ann Rheum Dis 69:561-6.
  5. Patsopoulos, NA, Evangelou, E, Ioannidis, JP. 2009. Heterogeneous views on heterogeneity. Int J Epidemiol 38:1740-2.
  6. Ioannidis, JP, Patsopoulos, NA, Rothstein, HR. 2008. Reasons or excuses for avoiding meta-analysis in forest plots. BMJ 336:1413-5.
  7. Yesupriya, A, Evangelou, E, Kavvoura, FK, Patsopoulos, NA, Clyne, M, Walsh, MC, Lin, BK, Yu, W, Gwinn, M, Ioannidis, JP, Khoury, MJ. 2008. Reporting of human genome epidemiology (HuGE) association studies: an empirical assessment. BMC Med Res Methodol 8:31.
  8. Patsopoulos, NA, Evangelou, E, Ioannidis, JP. 2008. Sensitivity of between-study heterogeneity in meta-analysis: proposed metrics and empirical evaluation. Int J Epidemiol 37:1148-57.
  9. Ioannidis, JP, Patsopoulos, NA, Evangelou, E. 2007. Uncertainty in heterogeneity estimates in meta-analyses. BMJ 335:914-6.
  10. Ioannidis, JP, Patsopoulos, NA, Kavvoura, FK, Tatsioni, A, Evangelou, E, Kouri, I, Contopoulos-Ioannidis, DG, Liberopoulos, G. 2007. International ranking systems for universities and institutions: a critical appraisal. BMC Med 5:30.
  11. Ioannidis, JP, Patsopoulos, NA, Evangelou, E. 2007. Heterogeneity in meta-analyses of genome-wide association investigations. PLoS One 2:e841.
  12. Patsopoulos, NA, Tatsioni, A, Ioannidis, JP. 2007. Claims of sex differences: an empirical assessment in genetic associations. JAMA 298:880-93.
  13. Patsopoulos, NA, Ioannidis, JP, Analatos, AA. 2006. Origin and funding of the most frequently cited papers in medicine: database analysis. BMJ 332:1061-4.
  14. Patsopoulos, NA, Analatos, AA, Ioannidis, JP. 2005. Relative citation impact of various study designs in the health sciences. JAMA 293:2362-6.
  15. Patsopoulos, NA, Ntzani, EE, Zintzaras, E, Ioannidis, JP. 2005. CYP2D6 polymorphisms and the risk of tardive dyskinesia in schizophrenia: a meta-analysis. Pharmacogenet Genomics 15:151-8.
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